Cohort: 2024
Country: Kenya
Focus Area: Global Immunology and Immune Sequencing for Epidemic Response(GIISER)
Dr Charles Sande focuses on the Respiratory Syncytial Virus, seeking to understand local immune response to the virus in the airway. Secondary interests include vaccinology, serology, and systems immunology. Most recently, Sande’s work has looked at the molecular mechanisms that predict adverse outcomes in African children admitted to the hospital with sepsis and other severe acute infections. He and his team deploy a wide array of systems tools, including proteomics, transcriptomics, and traditional protein microarrays. Their goal is to develop a fuller understanding of why some children have a significantly higher risk of dying shortly after admission to the hospital.