About the grantee

Bonomo’s expertise is in the cellular immunology of tolerance and T cells. She has demonstrated the role of thymic epithelium in central tolerance, the escape of unselected T cells in autoimmunity models, and the supportive function of T cells in bone metastases of breast tumors. Her group currently studies the influence of T cells in metastasis; oral tolerance using a probiotic as an adjuvant therapy to prevent Graft vs. Host disease, and, more recently, neuroimmunology of the developing brain and strategies to regulate neuroinflammation. Bonomo’s team studied select monoclonal antibodies in three human cohorts at the emergence of the COVID-19 pandemic: infected patients with household transmission evaluation in health workers and Chagas Disease in COVID-19 patients, looking at humoral, cellular and innate immunity.